There are no architecturial limitations towards changing IP addresses of storage nodes in a live cluster. However to change this a rolling upgrade must be performed. (This procedure should work also when needing to move a certain data node from one computer to another, in this case it is likely that the new node doesn't have the file system of the old node and thus ndbd --initial should be used on that node, not on the others). This is the procedure in this specific case. 1) Stop the management server 2) Start the management server with the new config file 3) Stop one data node at the time and restart it (the node to change IP address is restarted last) 4) Continue with step 4) until all nodes have been changed 5) Stop MySQL Servers one at a time and restart it 6) Continue with step 5) until all MySQL Servers have been restarted I haven't tried it myself so please report if it is successful or otherwise where it goes wrong.